What do the states mean?+
- Solid: well studied, and it works.
- Half-there: the science is still forming.
- A ghost: almost no real studies.
- Hollow: well studied, and it does not work.
- A cord: the pair itself has been tested together.
- Air: nobody has ever tested this pair.
The full scoring method: How we score
Can you take vitamin B12 and kava together?
Nobody has tested this pair.
As of August 2026, no human trial has given vitamin B12 and kava together. We searched PubMed for trials naming both on 26 August 2026 and read every candidate it returned; none tested the pair.
15 studies · none tested the actual pair · 2 cautions
See what each one is on its own
What you’re seeing
- Vitamin B12 renders half-there: for energy and fatigue, the science is still forming.
- Kava renders half-there: for stress and anxiety, the science is still forming.
- Nothing is drawn between them, because nothing has been run. The empty space is the review.
- The red spark: Kava has been linked to serious liver injury, and several countries restricted or banned its sale over it. Do not take kava if you have liver problems, and do not combine it with alcohol or with medicines processed by the liver. Talk to your doctor first.
You can tell before you read a word.
Vitamin D + vitamin K2 is what the other answer looks like. Someone ran the study, so a cord is drawn between them. That is the whole difference.
Fair questions
Is it safe to take vitamin B12 and kava together?+
No trial has tested the combination, so there is no evidence either way. Nobody has found a problem, and nobody has looked.
Why does this page say nobody has tested it?+
Because we ran the search and read the results. The date above is the day we ran it. We do not claim a pair is untested without a logged search behind it.
Will this page change?+
Yes, if a trial publishes. We re-run these searches and the page changes from air to a cord the day the evidence does.
Deeper
The search we ran+
On 26 August 2026 we asked PubMed for trials, reviews and meta-analyses naming both vitamin B12 and kava. It returned nothing. We read every one and none gave the two together. This page carries a date because the answer can change: if a trial publishes, the air becomes a cord.
What each one is on its own+
Vitamin B12
- Energy and fatiguehalf-there
- Anaemia and iron levelshalf-there
- Hearthollow
- Memory and focushollow
- Moodhollow
- Nerve painhalf-there
- Pregnancyhalf-there
- Sleephalf-there
- Stress and anxietyhalf-there
Kava
- Stress and anxietyhalf-there
Pairs that have been tested+
- Vitamin B12 has been tested with folate.
- Kava has been tested with St John’s wort, calcium.
These are the combinations someone has actually run a study on. Every other pairing here is air.
Worth knowing+
- Kava has been linked to serious liver injury, and several countries restricted or banned its sale over it. Do not take kava if you have liver problems, and do not combine it with alcohol or with medicines processed by the liver. Talk to your doctor first.
- Vitamin B12: Searching 21 health outcomes returned no trial of vitamin B12 on its own for any of them. This is not the same as a supplement nobody has studied. Vitamin B12 is a nutrient your body needs, and there is research on it. What that research is about is correcting a measured deficiency, and multi-vitamin formulations where B12 is one ingredient among many. None of it tells you whether taking extra helps someone who already gets enough.